Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington’s disease patients

In Huntington’s disease (HD), the mutant Huntingtin (mHTT) is postulated to mediate template-based aggregation that can propagate across cells. It has been difficult to quantitatively detect such pathological seeding activities in patient biosamples, e.g. cerebrospinal fluids (CSF), and study their...

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Detalles Bibliográficos
Autores principales: Lee, C. Y. Daniel, Wang, Nan, Shen, Koning, Stricos, Matthew, Langfelder, Peter, Cheon, Kristina H., Cortés, Etty P., Vinters, Harry V., Vonsattel, Jean Paul, Wexler, Nancy S., Damoiseaux, Robert, Frydman, Judith, Yang, X. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679413/
https://www.ncbi.nlm.nih.gov/pubmed/33219289
http://dx.doi.org/10.1038/s41598-020-77164-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679413/
https://www.ncbi.nlm.nih.gov/pubmed/33219289
http://dx.doi.org/10.1038/s41598-020-77164-1

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