Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases

Mitosis has been validated by numerous anti-cancer drugs as being a druggable process, and selective inhibition of parasite proliferation provides an obvious opportunity for therapeutic intervention against malaria. Mitosis is controlled through the interplay between several protein kinases and phos...

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Detalles Bibliográficos
Autores principales: Morahan, Belinda J., Abrie, Clarissa, Al-Hasani, Keith, Batty, Mitchell B., Corey, Victoria, Cowell, Anne N., Niemand, Jandeli, Winzeler, Elizabeth A., Birkholtz, Lyn-Marie, Doerig, Christian, Garcia-Bustos, Jose F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679417/
https://www.ncbi.nlm.nih.gov/pubmed/33219324
http://dx.doi.org/10.1038/s42003-020-01424-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679417/
https://www.ncbi.nlm.nih.gov/pubmed/33219324
http://dx.doi.org/10.1038/s42003-020-01424-z

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