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Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication

Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a positive correlation between iNos and Tnfα mRNA and Ptn mRNA levels in the prefrontal cortex (PFC) of LPS-treated mice....

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Detalles Bibliográficos
Autores principales: Fernández-Calle, Rosalía, Galán-Llario, Milagros, Gramage, Esther, Zapatería, Begoña, Vicente-Rodríguez, Marta, Zapico, José M., de Pascual-Teresa, Beatriz, Ramos, Ana, Ramos-Álvarez, M. Pilar, Uribarri, María, Ferrer-Alcón, Marcel, Herradón, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679445/
https://www.ncbi.nlm.nih.gov/pubmed/33219280
http://dx.doi.org/10.1038/s41598-020-76415-5