Cargando…
Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication
Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a positive correlation between iNos and Tnfα mRNA and Ptn mRNA levels in the prefrontal cortex (PFC) of LPS-treated mice....
Autores principales: | Fernández-Calle, Rosalía, Galán-Llario, Milagros, Gramage, Esther, Zapatería, Begoña, Vicente-Rodríguez, Marta, Zapico, José M., de Pascual-Teresa, Beatriz, Ramos, Ana, Ramos-Álvarez, M. Pilar, Uribarri, María, Ferrer-Alcón, Marcel, Herradón, Gonzalo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679445/ https://www.ncbi.nlm.nih.gov/pubmed/33219280 http://dx.doi.org/10.1038/s41598-020-76415-5 |
Ejemplares similares
-
Implication of the PTN/RPTPβ/ζ Signaling Pathway in Acute Ethanol Neuroinflammation in Both Sexes: A Comparative Study with LPS
por: Rodríguez-Zapata, María, et al.
Publicado: (2023) -
Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development
por: Herradon, Gonzalo, et al.
Publicado: (2019) -
Pleiotrophin regulates microglia-mediated neuroinflammation
por: Fernández-Calle, Rosalía, et al.
Publicado: (2017) -
Role of Receptor Protein Tyrosine Phosphatase β/ζ in Neuron–Microglia Communication in a Cellular Model of Parkinson’s Disease
por: del Campo, Marta, et al.
Publicado: (2021) -
Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease
por: Gramage, Esther, et al.
Publicado: (2022)