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Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

BACKGROUND: Due to the lack of protective immunity of humans towards the newly emerged SARS-CoV-2, this virus has caused a massive pandemic across the world resulting in hundreds of thousands of deaths. Thus, a vaccine is urgently needed to contain the spread of the virus. METHODS: Here, we describe...

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Detalles Bibliográficos
Autores principales: Sun, Weina, Leist, Sarah R., McCroskery, Stephen, Liu, Yonghong, Slamanig, Stefan, Oliva, Justine, Amanat, Fatima, Schäfer, Alexandra, Dinnon, Kenneth H., García-Sastre, Adolfo, Krammer, Florian, Baric, Ralph S., Palese, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679520/
https://www.ncbi.nlm.nih.gov/pubmed/33232870
http://dx.doi.org/10.1016/j.ebiom.2020.103132