The KINGS Ins2(+/G32S) Mouse: A Novel Model of β-Cell Endoplasmic Reticulum Stress and Human Diabetes

Animal models are important tools in diabetes research because ethical and logistical constraints limit access to human tissue. β-Cell dysfunction is a common contributor to the pathogenesis of most types of diabetes. Spontaneous hyperglycemia was developed in a colony of C57BL/6J mice at King’s Col...

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Detalles Bibliográficos
Autores principales: Austin, Amazon L.F., Daniels Gatward, Lydia F., Cnop, Miriam, Santos, Gabriel, Andersson, David, Sharp, Sally, Gentry, Clive, Bevan, Stuart, Jones, Peter M., King, Aileen J.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2020
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679781/
https://www.ncbi.nlm.nih.gov/pubmed/32994272
http://dx.doi.org/10.2337/db20-0570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679781/
https://www.ncbi.nlm.nih.gov/pubmed/32994272
http://dx.doi.org/10.2337/db20-0570

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