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Ligand binding and global adaptation of the GlnPQ substrate binding domain 2 revealed by molecular dynamics simulations

Substrate‐binding domains (SBD) are important structural elements of substrate transporters mediating the transport of essential molecules across the cell membrane. The SBD2 domain of the glutamine (GLN) transporter from bacteria consists of two domains D1 and D2 that bind GLN in the space between t...

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Detalles Bibliográficos
Autores principales: Kienlein, Maximilian, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679957/
https://www.ncbi.nlm.nih.gov/pubmed/33070437
http://dx.doi.org/10.1002/pro.3981