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STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells

BACKGROUND: In mammals, it is known that the estradiol-17β (E2) is mainly synthetized in ovarian granulosa cells (GCs), and the excessive apoptosis of GCs induces the follicular atresia. Many studies have implicated the essential role of KISS1, with the pro-synthetic effect of E2 and the anti-apopto...

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Detalles Bibliográficos
Autores principales: Jiang, Yao, Xin, Xiaoping, Pan, Xiangchun, Zhang, Ailing, Zhang, Zhe, Li, Jiaqi, Yuan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679982/
https://www.ncbi.nlm.nih.gov/pubmed/33218349
http://dx.doi.org/10.1186/s13048-020-00741-5