Technical validation of a new microfluidic device for enrichment of CTCs from large volumes of blood by using buffy coats to mimic diagnostic leukapheresis products

Diagnostic leukapheresis (DLA) enables to sample larger blood volumes and increases the detection of circulating tumor cells (CTC) significantly. Nevertheless, the high excess of white blood cells (WBC) of DLA products remains a major challenge for further downstream CTC enrichment and detection. To...

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Detalles Bibliográficos
Autores principales: Guglielmi, R., Lai, Z., Raba, K., van Dalum, G., Wu, J., Behrens, B., Bhagat, A. A. S., Knoefel, W. T., Neves, R. P. L., Stoecklein, N. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680114/
https://www.ncbi.nlm.nih.gov/pubmed/33219265
http://dx.doi.org/10.1038/s41598-020-77227-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680114/
https://www.ncbi.nlm.nih.gov/pubmed/33219265
http://dx.doi.org/10.1038/s41598-020-77227-3

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