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Technical validation of a new microfluidic device for enrichment of CTCs from large volumes of blood by using buffy coats to mimic diagnostic leukapheresis products
Diagnostic leukapheresis (DLA) enables to sample larger blood volumes and increases the detection of circulating tumor cells (CTC) significantly. Nevertheless, the high excess of white blood cells (WBC) of DLA products remains a major challenge for further downstream CTC enrichment and detection. To...
Autores principales: | Guglielmi, R., Lai, Z., Raba, K., van Dalum, G., Wu, J., Behrens, B., Bhagat, A. A. S., Knoefel, W. T., Neves, R. P. L., Stoecklein, N. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680114/ https://www.ncbi.nlm.nih.gov/pubmed/33219265 http://dx.doi.org/10.1038/s41598-020-77227-3 |
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