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Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation

Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order organization of more than one nucleosome. We show the yeast ISW1a remodeler has such higher-order structural specificity, as manifested by l...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Saurabh K., Hailu, Solomon G., Olufemi, Lola, Brahma, Sandipan, Kundu, Soumyadipta, Hota, Swetansu K., Persinger, Jim, Bartholomew, Blaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680125/
https://www.ncbi.nlm.nih.gov/pubmed/33219211
http://dx.doi.org/10.1038/s41467-020-19700-1