ROCK inhibitors beneficially alter the spatial configuration of TGFβ2-treated 3D organoids from a human trabecular meshwork (HTM)

To elucidate molecular pharmacology of Rho-associated coiled-coil containing protein kinase inhibitors (ROCK-i, Ripasudil and Y27632) on their efficiency for aqueous outflow, 2D or 3D cultures of a human trabecular meshwork (HTM) were prepared in the presence of TGFβ2. Those were examined by transen...

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Detalles Bibliográficos
Autores principales: Ota, Chiaki, Ida, Yosuke, Ohguro, Hiroshi, Hikage, Fumihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680137/
https://www.ncbi.nlm.nih.gov/pubmed/33219246
http://dx.doi.org/10.1038/s41598-020-77302-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680137/
https://www.ncbi.nlm.nih.gov/pubmed/33219246
http://dx.doi.org/10.1038/s41598-020-77302-9

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