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Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes

Hypothalamic inflammation plays an important role in disrupting feeding behavior and energy homeostasis as well as in the pathogenesis of obesity and diabetes. Here, we show that pyruvate dehydrogenase kinase (PDK)-2 plays a role in hypothalamic inflammation and its sequelae in mouse models of diabe...

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Detalles Bibliográficos
Autores principales: Rahman, Md Habibur, Bhusal, Anup, Kim, Jae-Hong, Jha, Mithilesh Kumar, Song, Gyun Jee, Go, Younghoon, Jang, Il-Sung, Lee, In-Kyu, Suk, Kyoungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680139/
https://www.ncbi.nlm.nih.gov/pubmed/33219201
http://dx.doi.org/10.1038/s41467-020-19576-1