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Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of Infections to Navigate Epidemics), a sensitive and specific diagnostic tool that can detect SARS-CoV-2 RNA from unextracted s...

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Detalles Bibliográficos
Autores principales: Arizti-Sanz, Jon, Freije, Catherine A., Stanton, Alexandra C., Petros, Brittany A., Boehm, Chloe K., Siddiqui, Sameed, Shaw, Bennett M., Adams, Gordon, Kosoko-Thoroddsen, Tinna-Solveig F., Kemball, Molly E., Uwanibe, Jessica N., Ajogbasile, Fehintola V., Eromon, Philomena E., Gross, Robin, Wronka, Loni, Caviness, Katie, Hensley, Lisa E., Bergman, Nicholas H., MacInnis, Bronwyn L., Happi, Christian T., Lemieux, Jacob E., Sabeti, Pardis C., Myhrvold, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680145/
https://www.ncbi.nlm.nih.gov/pubmed/33219225
http://dx.doi.org/10.1038/s41467-020-19097-x