Clinical evaluation of [(18)F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer’s disease

PURPOSE: The accumulation of misfolded tau is a common feature of several neurodegenerative disorders, with Alzheimer’s disease (AD) being the most common. Earlier we identified JNJ-64326067, a novel isoquinoline derivative with high affinity and selectivity for tau aggregates from human AD brain. W...

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Detalles Bibliográficos
Autores principales: Schmidt, Mark E., Janssens, Luc, Moechars, Diederik, Rombouts, Frederik J. R., Timmers, Maarten, Barret, Olivier, Constantinescu, Cristian C., Madonia, Jennifer, Russell, David S., Sandiego, Christine M., Kolb, Hartmuth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680304/
https://www.ncbi.nlm.nih.gov/pubmed/32535652
http://dx.doi.org/10.1007/s00259-020-04880-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680304/
https://www.ncbi.nlm.nih.gov/pubmed/32535652
http://dx.doi.org/10.1007/s00259-020-04880-1

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