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A perspective on the early days of RAS research

The name of the oncogene, ras, has its origin in studies of murine leukemia viruses in the 1960s by Jenny Harvey (H-ras) and by Werner Kirsten (K-ras) which, at high doses, produced sarcomas in rats. Transforming retroviruses were isolated, and its oncogene was named ras after rat sarcoma. From 1979...

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Detalles Bibliográficos
Autor principal: Weiss, Robin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680315/
https://www.ncbi.nlm.nih.gov/pubmed/32728828
http://dx.doi.org/10.1007/s10555-020-09919-1