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Molecular epidemiology and diagnostics of KRAS mutations in human cancer

RAS mutation is the most frequent oncogenic alteration in human cancers. KRAS is the most frequently mutated followed by NRAS. The emblematic KRAS mutant cancers are pancreatic, colorectal, lung adenocarcinomas and urogenital cancers. KRAS mutation frequencies are relatively stable worldwide in vari...

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Detalles Bibliográficos
Autores principales: Timar, Jozsef, Kashofer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680318/
https://www.ncbi.nlm.nih.gov/pubmed/32725342
http://dx.doi.org/10.1007/s10555-020-09915-5