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Small molecule inhibitors of RAS proteins with oncogenic mutations
RAS proteins control a number of essential cellular processes as molecular switches in the human body. Presumably due to their important signalling role, RAS proteins are among the most frequently mutated oncogenes in human cancers. Hence, numerous efforts were done to develop appropriate therapies...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680341/ https://www.ncbi.nlm.nih.gov/pubmed/32770300 http://dx.doi.org/10.1007/s10555-020-09911-9 |