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Chemoselective α-Sulfidation of Amides Using Sulfoxide Reagents

[Image: see text] The direct α-sulfidation of tertiary amides using sulfoxide reagents under electrophilic amide activation conditions is described. Employing convenient and readily available reagents, selective functionalization takes place to generate isolable sulfonium ions en route to α-sulfide...

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Detalles Bibliográficos
Autores principales: Leypold, Mario, D’Angelo, Kyan A., Movassaghi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680396/
https://www.ncbi.nlm.nih.gov/pubmed/33048547
http://dx.doi.org/10.1021/acs.orglett.0c03160