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WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer that lacks the oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, making it difficult to target therapeutically. Targeting synthetic lethality is an alternative approach for cancer...

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Detalles Bibliográficos
Autores principales: Ertay, Ayse, Liu, Huiquan, Liu, Dian, Peng, Ping, Hill, Charlotte, Xiong, Hua, Hancock, David, Yuan, Xianglin, Przewloka, Marcin R., Coldwell, Mark, Howell, Michael, Skipp, Paul, Ewing, Rob M., Downward, Julian, Wang, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680459/
https://www.ncbi.nlm.nih.gov/pubmed/33221821
http://dx.doi.org/10.1038/s41419-020-03210-5