Depletion of GPSM1 enhances ovarian granulosa cell apoptosis via cAMP-PKA-CREB pathway in vitro

BACKGROUND: Genetic causes of premature ovarian insufficiency (POI) account for approximately 20 ~ 25% of patients. So far, only a few genes have been identified. RESULTS: Here, we first identified the c.1840C > A on G-protein signaling modulator 1 (GPSM1) as a susceptibility locus for POI in 10...

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Detalles Bibliográficos
Autores principales: Cai, Xuzi, Fu, Huijiao, Wang, Yan, Liu, Qiwen, Wang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680585/
https://www.ncbi.nlm.nih.gov/pubmed/33220708
http://dx.doi.org/10.1186/s13048-020-00740-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680585/
https://www.ncbi.nlm.nih.gov/pubmed/33220708
http://dx.doi.org/10.1186/s13048-020-00740-6

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