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Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability

PURPOSE: The aim of the studies was to fabricate aceclofenac (AC) tablets using nanosuspension as granulating fluid to boost its rate of in vitro dissolution and eventually its oral bioavailability. METHODS: The optimized nanosuspension with particle size of 112±2.01 nm was fabricated using HPMC 1%...

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Detalles Bibliográficos
Autores principales: Rahim, Haroon, Sadiq, Abdul, Ullah, Riaz, Bari, Ahmed, Amin, Fazli, Farooq, Umar, Ullah Jan, Naeem, Mahmood, Hafiz Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680606/
https://www.ncbi.nlm.nih.gov/pubmed/33235448
http://dx.doi.org/10.2147/IJN.S270746