Acute administration of nicotine induces transient elevation of blood pressure and increases myocardial infarct size in rats

AIMS: We investigated the acute effects of nicotine on myocardial infarct size, no reflow, hemodynamics and cardiac function in an acute myocardial ischemia and reperfusion infarction rat model. MAIN METHODS: Female Sprague-Dawley rats (n = 23/group) received an intravenous loading dose of nicotine...

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Detalles Bibliográficos
Autores principales: Zhao, Lifu, Dai, Wangde, Carreno, Juan, Shi, Jianru, Kleinman, Michael T., Kloner, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680768/
https://www.ncbi.nlm.nih.gov/pubmed/33251352
http://dx.doi.org/10.1016/j.heliyon.2020.e05450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680768/
https://www.ncbi.nlm.nih.gov/pubmed/33251352
http://dx.doi.org/10.1016/j.heliyon.2020.e05450

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