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Acute administration of nicotine induces transient elevation of blood pressure and increases myocardial infarct size in rats
AIMS: We investigated the acute effects of nicotine on myocardial infarct size, no reflow, hemodynamics and cardiac function in an acute myocardial ischemia and reperfusion infarction rat model. MAIN METHODS: Female Sprague-Dawley rats (n = 23/group) received an intravenous loading dose of nicotine...
Autores principales: | Zhao, Lifu, Dai, Wangde, Carreno, Juan, Shi, Jianru, Kleinman, Michael T., Kloner, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680768/ https://www.ncbi.nlm.nih.gov/pubmed/33251352 http://dx.doi.org/10.1016/j.heliyon.2020.e05450 |
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