Loss of Drosophila E3 Ubiquitin Ligase Hyd Promotes Extra Mitosis in Germline Cysts and Massive Cell Death During Oogenesis

The Drosophila hyperplastic disc (hyd) gene is the ortholog of mammalian tumor suppressor EDD, which is implicated in a wide variety of cellular processes, and its regulation is impaired in various tumors. It is a member of the highly conserved HECT family of E3 ubiquitin ligases, which directly att...

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Detalles Bibliográficos
Autores principales: Dorogova, Natalia V., Galimova, Yuliya A., Bolobolova, Elena Us., Baricheva, Elina M., Fedorova, Svetlana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680892/
https://www.ncbi.nlm.nih.gov/pubmed/33240894
http://dx.doi.org/10.3389/fcell.2020.600868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680892/
https://www.ncbi.nlm.nih.gov/pubmed/33240894
http://dx.doi.org/10.3389/fcell.2020.600868

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