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Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies: A Combination of Intrinsic Genomic Instability and Exocytosis Defects at the Immunological Synapse

Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence, or a malfunction of at least one part of the immune system. As a result, PID patients are more prone to develop life-threatening complications...

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Detalles Bibliográficos
Autores principales: Mastio, Jérôme, Saeed, Mezida B., Wurzer, Hannah, Krecke, Max, Westerberg, Lisa S., Thomas, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680899/
https://www.ncbi.nlm.nih.gov/pubmed/33240268
http://dx.doi.org/10.3389/fimmu.2020.581119