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Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies: A Combination of Intrinsic Genomic Instability and Exocytosis Defects at the Immunological Synapse
Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence, or a malfunction of at least one part of the immune system. As a result, PID patients are more prone to develop life-threatening complications...
Autores principales: | Mastio, Jérôme, Saeed, Mezida B., Wurzer, Hannah, Krecke, Max, Westerberg, Lisa S., Thomas, Clément |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680899/ https://www.ncbi.nlm.nih.gov/pubmed/33240268 http://dx.doi.org/10.3389/fimmu.2020.581119 |
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