Haploinsufficiency of Dspp Gene Causes Dentin Dysplasia Type II in Mice

Dentin dysplasia (DD) and dentinogenesis imperfecta (DGI) patients have abnormal structure, morphology, and function of dentin. DD-II, DGI-II, and DGI-III are caused by heterozygous mutations in the dentin sialophosphoprotein (DSPP) gene in humans. Evidences have shown that loss of function of DSPP...

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Detalles Bibliográficos
Autores principales: Shi, Ce, Ma, Ning, Zhang, Wei, Ye, Jiapeng, Shi, Haibo, Xiang, Danwei, Wu, Chunyue, Song, Lina, Zhang, Ning, Liu, Qilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680915/
https://www.ncbi.nlm.nih.gov/pubmed/33240110
http://dx.doi.org/10.3389/fphys.2020.593626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680915/
https://www.ncbi.nlm.nih.gov/pubmed/33240110
http://dx.doi.org/10.3389/fphys.2020.593626

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