Autologous non‐human primate model for safety assessment of piggyBac transposon‐mediated chimeric antigen receptor T cells on granulocyte–macrophage colony‐stimulating factor receptor

OBJECTIVES: Chimeric antigen receptor (CAR)‐T cell therapy redirected to specific antigens on tumor cells is a promising immunotherapy strategy for various cancers. Most target antigens are also expressed on normal tissues at varying levels, and therefore, a considerable challenge in the field is de...

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Detalles Bibliográficos
Autores principales: Morokawa, Hirokazu, Yagyu, Shigeki, Hasegawa, Aiko, Tanaka, Miyuki, Saito, Shoji, Mochizuki, Hidemi, Sakamoto, Kengo, Shimoi, Akihito, Nakazawa, Yozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680920/
https://www.ncbi.nlm.nih.gov/pubmed/33251009
http://dx.doi.org/10.1002/cti2.1207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680920/
https://www.ncbi.nlm.nih.gov/pubmed/33251009
http://dx.doi.org/10.1002/cti2.1207

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