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A physical basis for quantitative ChIP-sequencing

ChIP followed by next-generation sequencing (ChIP-Seq) is a key technique for mapping the distribution of histone posttranslational modifications (PTMs) and chromatin-associated factors across genomes. There is a perceived challenge to define a quantitative scale for ChIP-Seq data, and as such, seve...

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Detalles Bibliográficos
Autores principales: Dickson, Bradley M., Tiedemann, Rochelle L., Chomiak, Alison A., Cornett, Evan M., Vaughan, Robert M., Rothbart, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681007/
https://www.ncbi.nlm.nih.gov/pubmed/32994221
http://dx.doi.org/10.1074/jbc.RA120.015353