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Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis

Impaired clearance in the Alzheimer's Disease (AD) brain is key in the formation of Aβ parenchymal plaques and cerebrovascular deposits known as cerebral amyloid angiopathy (CAA), present in >80% of AD patients and ~50% of non‐AD elderly subjects. Aβ deposits are highly heterogeneous, contai...

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Detalles Bibliográficos
Autores principales: Parodi‐Rullán, Rebecca, Ghiso, Jorge, Cabrera, Erwin, Rostagno, Agueda, Fossati, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681048/
https://www.ncbi.nlm.nih.gov/pubmed/33155752
http://dx.doi.org/10.1111/acel.13258