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CR reprograms acetyl‐CoA metabolism and induces long‐chain acyl‐CoA dehydrogenase and CrAT expression

Calorie restriction (CR), an age delaying diet, affects fat oxidation through poorly understood mechanisms. We investigated the effect of CR on fat metabolism gene expression and intermediate metabolites of fatty acid oxidation in the liver. We found that CR changed the liver acylcarnitine profile:...

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Detalles Bibliográficos
Autores principales: Mezhnina, Volha, Pearce, Ryan, Poe, Allan, Velingkaar, Nikkhil, Astafev, Artem, Ebeigbe, Oghogho P., Makwana, Kuldeep, Sandlers, Yana, Kondratov, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681051/
https://www.ncbi.nlm.nih.gov/pubmed/33105059
http://dx.doi.org/10.1111/acel.13266