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CR reprograms acetyl‐CoA metabolism and induces long‐chain acyl‐CoA dehydrogenase and CrAT expression
Calorie restriction (CR), an age delaying diet, affects fat oxidation through poorly understood mechanisms. We investigated the effect of CR on fat metabolism gene expression and intermediate metabolites of fatty acid oxidation in the liver. We found that CR changed the liver acylcarnitine profile:...
Autores principales: | Mezhnina, Volha, Pearce, Ryan, Poe, Allan, Velingkaar, Nikkhil, Astafev, Artem, Ebeigbe, Oghogho P., Makwana, Kuldeep, Sandlers, Yana, Kondratov, Roman V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681051/ https://www.ncbi.nlm.nih.gov/pubmed/33105059 http://dx.doi.org/10.1111/acel.13266 |
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