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Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age

Hematopoietic stem cells (HSCs) maintain balanced blood cell production in a process called hematopoiesis. As humans age, their HSCs acquire mutations that allow some HSCs to disproportionately contribute to normal blood production. This process, known as age‐related clonal hematopoiesis, predispose...

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Detalles Bibliográficos
Autores principales: Grenier‐Pleau, Isabelle, Tyryshkin, Kathrin, Le, Tri Dung, Rudan, John, Bonneil, Eric, Thibault, Pierre, Zeng, Karen, Lässer, Cecilia, Mallinson, David, Lamprou, Dimitrios, Hui, Jialui, Postovit, Lynne‐Marie, Chan, Edmond Y. W., Abraham, Sheela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681054/
https://www.ncbi.nlm.nih.gov/pubmed/33029858
http://dx.doi.org/10.1111/acel.13245