Transformation of resident notochord‐descendent nucleus pulposus cells in mouse injury‐induced fibrotic intervertebral discs

Intervertebral disc degeneration (IDD), a major cause of low back pain, occurs with ageing. The core of the intervertebral disc, the nucleus pulposus (NP), embedded in a proteoglycan‐rich and gelatinous matrix, is derived from the embryonic notochord. With IDD, the NP becomes fibrous, containing few...

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Detalles Bibliográficos
Autores principales: Au, Tiffany Y. K., Lam, To‐Kam, Peng, Yan, Wynn, Sarah L., Cheung, Kenneth M. C., Cheah, Kathryn S. E., Leung, Victor Y. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681061/
https://www.ncbi.nlm.nih.gov/pubmed/33084203
http://dx.doi.org/10.1111/acel.13254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681061/
https://www.ncbi.nlm.nih.gov/pubmed/33084203
http://dx.doi.org/10.1111/acel.13254

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