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Transformation of resident notochord‐descendent nucleus pulposus cells in mouse injury‐induced fibrotic intervertebral discs

Intervertebral disc degeneration (IDD), a major cause of low back pain, occurs with ageing. The core of the intervertebral disc, the nucleus pulposus (NP), embedded in a proteoglycan‐rich and gelatinous matrix, is derived from the embryonic notochord. With IDD, the NP becomes fibrous, containing few...

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Detalles Bibliográficos
Autores principales:	Au, Tiffany Y. K., Lam, To‐Kam, Peng, Yan, Wynn, Sarah L., Cheung, Kenneth M. C., Cheah, Kathryn S. E., Leung, Victor Y. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Short Takes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681061/ https://www.ncbi.nlm.nih.gov/pubmed/33084203 http://dx.doi.org/10.1111/acel.13254

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