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A role for intestinal alkaline phosphatase in preventing liver fibrosis

Rationale: Liver fibrosis is frequently associated with gut barrier dysfunction, and the lipopolysaccharides (LPS) -TLR4 pathway is common to the development of both. Intestinal alkaline phosphatase (IAP) has the ability to detoxify LPS, as well as maintain intestinal tight junction proteins and gut...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Cavallaro, Paul M., Kim, Byeong-Moo, Liu, Tao, Wang, Hongyan, Kühn, Florian, Adiliaghdam, Fatemeh, Liu, Enyu, Vasan, Robin, Samarbafzadeh, Ehsan, Farber, Matthew Z., Li, Junhui, Xu, Meng, Mohad, Vidisha, Choi, Michael, Hodin, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681079/
https://www.ncbi.nlm.nih.gov/pubmed/33391458
http://dx.doi.org/10.7150/thno.48468