Progenitor cell-derived exosomes endowed with VEGF plasmids enhance osteogenic induction and vascular remodeling in large segmental bone defects

Large segmental bone regeneration remains a great challenge due to the lack of vascularization in newly formed bone. Conventional strategies primarily combine bone scaffolds with seed cells and growth factors to modulate osteogenesis and angiogenesis. Nevertheless, cell-based therapies have some int...

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Detalles Bibliográficos
Autores principales: Zha, Yao, Li, Yawu, Lin, Tianyi, Chen, Jia, Zhang, Shengmin, Wang, Jianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681080/
https://www.ncbi.nlm.nih.gov/pubmed/33391482
http://dx.doi.org/10.7150/thno.50741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681080/
https://www.ncbi.nlm.nih.gov/pubmed/33391482
http://dx.doi.org/10.7150/thno.50741

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