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Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice

Background: Understanding the molecular events and mechanisms underlying development and progression of nonalcoholic steatohepatitis is essential in an attempt to formulating a specific treatment. Here, we uncover Platr4 as an oscillating and NF-κB driven lncRNA that is critical to the pathological...

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Detalles Bibliográficos
Autores principales: Lin, Yanke, Wang, Shuai, Gao, Lu, Zhou, Ziyue, Yang, Zemin, Lin, Jingpan, Ren, Shujing, Xing, Huijie, Wu, Baojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681083/
https://www.ncbi.nlm.nih.gov/pubmed/33391484
http://dx.doi.org/10.7150/thno.50281