tRNA-derived fragments: Mechanisms underlying their regulation of gene expression and potential applications as therapeutic targets in cancers and virus infections

tRNA-derived fragments (tRFs) are a new category of regulatory noncoding RNAs with distinct biological functions in cancers and stress-induced diseases. Herein, we first summarize the classification and biogenesis of tRFs. tRFs are produced from pre-tRNAs or mature tRNAs. Based on the incision loci,...

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Detalles Bibliográficos
Autores principales: Yu, Xiuchong, Xie, Yaoyao, Zhang, Shuangshuang, Song, Xuemei, Xiao, Bingxiu, Yan, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681095/
https://www.ncbi.nlm.nih.gov/pubmed/33391486
http://dx.doi.org/10.7150/thno.51963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681095/
https://www.ncbi.nlm.nih.gov/pubmed/33391486
http://dx.doi.org/10.7150/thno.51963

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