The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential

Objectives: Mesenchymal Stem/Stromal Cells (MSC) are promising therapeutic tools for inflammatory diseases due to their potent immunoregulatory capacities. Their suppressive activity mainly depends on inflammatory cues that have been recently associated with changes in MSC bioenergetic status toward...

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Detalles Bibliográficos
Autores principales: Contreras-Lopez, Rafael, Elizondo-Vega, Roberto, Luque-Campos, Noymar, Torres, María José, Pradenas, Carolina, Tejedor, Gautier, Paredes-Martínez, María José, Vega-Letter, Ana María, Campos-Mora, Mauricio, Rigual-Gonzalez, Yandi, Oyarce, Karina, Salgado, Magdiel, Jorgensen, Christian, Khoury, Maroun, Garcia-Robles, María de los Ángeles, Altamirano, Claudia, Djouad, Farida, Luz-Crawford, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681096/
https://www.ncbi.nlm.nih.gov/pubmed/33391485
http://dx.doi.org/10.7150/thno.51631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681096/
https://www.ncbi.nlm.nih.gov/pubmed/33391485
http://dx.doi.org/10.7150/thno.51631

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