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The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
Objectives: Mesenchymal Stem/Stromal Cells (MSC) are promising therapeutic tools for inflammatory diseases due to their potent immunoregulatory capacities. Their suppressive activity mainly depends on inflammatory cues that have been recently associated with changes in MSC bioenergetic status toward...
Autores principales: | Contreras-Lopez, Rafael, Elizondo-Vega, Roberto, Luque-Campos, Noymar, Torres, María José, Pradenas, Carolina, Tejedor, Gautier, Paredes-Martínez, María José, Vega-Letter, Ana María, Campos-Mora, Mauricio, Rigual-Gonzalez, Yandi, Oyarce, Karina, Salgado, Magdiel, Jorgensen, Christian, Khoury, Maroun, Garcia-Robles, María de los Ángeles, Altamirano, Claudia, Djouad, Farida, Luz-Crawford, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681096/ https://www.ncbi.nlm.nih.gov/pubmed/33391485 http://dx.doi.org/10.7150/thno.51631 |
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