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Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum

AIMS: Psychosis spectrum disorder has a complex pathoetiology characterised by interacting environmental and genetic vulnerabilities. The present study aims to investigate the role of gene–environment interaction using aggregate scores of genetic (polygenic risk score for schizophrenia (PRS-SCZ)) an...

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Detalles Bibliográficos
Autores principales: Pries, L.-K., Dal Ferro, G. A., van Os, J., Delespaul, P., Kenis, G., Lin, B. D., Luykx, J. J., Richards, A. L., Akdede, B., Binbay, T., Altınyazar, V., Yalınçetin, B., Gümüş-Akay, G., Cihan, B., Soygür, H., Ulaş, H., Şahin Cankurtaran, E., Ulusoy Kaymak, S., Mihaljevic, M. M., Andric Petrovic, S., Mirjanic, T., Bernardo, M., Mezquida, G., Amoretti, S., Bobes, J., Saiz, P. A., García-Portilla, M. Paz, Sanjuan, J., Aguilar, E. J., Santos, J. L., Jiménez-López, E., Arrojo, M., Carracedo, A., López, G., González-Peñas, J., Parellada, M., Maric, N. P., Atbaşoğlu, C., Ucok, A., Alptekin, K., Can Saka, M., Arango, C., O'Donovan, M., Tosato, S., Rutten, B. P. F., Guloksuz, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681168/
https://www.ncbi.nlm.nih.gov/pubmed/33200977
http://dx.doi.org/10.1017/S2045796020000943