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Inhibitor for protein disulfide-isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

mTOR is involved in the proliferation of liver cancer. However, the clinical benefit of treatment with mTOR inhibitors for liver cancer is controversial. Protein disulfide isomerase A member 3 (PDIA3) is a chaperone protein, and it supports the assembly of mTOR complex 1 (mTORC1) and stabilizes sign...

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Detalles Bibliográficos
Autores principales: Kaneya, Yohei, Takata, Hideyuki, Wada, Ryuichi, Kure, Shoko, Ishino, Kousuke, Kudo, Mitsuhiro, Kondo, Ryota, Taniai, Nobuhiko, Ohashi, Ryuji, Yoshida, Hiroshi, Naito, Zenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681208/
https://www.ncbi.nlm.nih.gov/pubmed/33240434
http://dx.doi.org/10.3892/ol.2020.12289