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Downregulation of histone-lysine N-methyltransferase EZH2 inhibits cell viability and enhances chemosensitivity in lung cancer cells

Histone-lysine N-methyltransferase EZH2 (EZH2) is the principle component of the polycomb repressive complex 2 (PRC2)/embryonic ectoderm development protein-EZH2 complex, which promotes tumorigenesis by repressing transcription of tumor suppressor genes. EZH2 is considered a key marker in several ty...

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Detalles Bibliográficos
Autores principales: Cao, Ziyang, Wu, Wei, Wei, Haiting, Zhang, Wei, Huang, Yan, Dong, Zhengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681225/
https://www.ncbi.nlm.nih.gov/pubmed/33240432
http://dx.doi.org/10.3892/ol.2020.12287