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A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology

OBJECTIVE: Transgenic re‐expression enables unbiased investigation of T‐cell receptor (TCR)‐intrinsic characteristics detached from its original cellular context. Recent advancements in TCR repertoire sequencing and development of protocols for direct cloning of full TCRαβ constructs now facilitate...

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Detalles Bibliográficos
Autores principales: Müller, Thomas R, Schuler, Corinna, Hammel, Monika, Köhler, Amelie, Jutz, Sabrina, Leitner, Judith, Schober, Kilian, Busch, Dirk H, Steinberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681835/
https://www.ncbi.nlm.nih.gov/pubmed/33251011
http://dx.doi.org/10.1002/cti2.1216