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A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology
OBJECTIVE: Transgenic re‐expression enables unbiased investigation of T‐cell receptor (TCR)‐intrinsic characteristics detached from its original cellular context. Recent advancements in TCR repertoire sequencing and development of protocols for direct cloning of full TCRαβ constructs now facilitate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681835/ https://www.ncbi.nlm.nih.gov/pubmed/33251011 http://dx.doi.org/10.1002/cti2.1216 |