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N(6)-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

BACKGROUND AND AIMS: Accumulating evidence suggests that the primary and acquired resistance of hepatocellular carcinoma (HCC) to sorafenib is mediated by multiple molecular, cellular, and microenvironmental mechanisms. Understanding these mechanisms will enhance the likelihood of effective sorafeni...

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Detalles Bibliográficos
Autores principales: Xu, Junjie, Wan, Zhe, Tang, Minyue, Lin, Zhongjie, Jiang, Shi, Ji, Lin, Gorshkov, Kirill, Mao, Qijiang, Xia, Shunjie, Cen, Dong, Zheng, Junhao, Liang, Xiao, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681956/
https://www.ncbi.nlm.nih.gov/pubmed/33222692
http://dx.doi.org/10.1186/s12943-020-01281-8