Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology

The brain pathology of Alzheimer’s disease (AD) is characterized by the misfolding and aggregation of both the amyloid beta (Aβ) peptide and hyperphosphorylated forms of the tau protein. Initial Aβ deposition is considered to trigger a sequence of deleterious events contributing to tau pathology, ne...

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Detalles Bibliográficos
Autores principales: Laversenne, Vanessa, Nazeeruddin, Sameer, Källstig, Emma C., Colin, Philippe, Voize, Christel, Schneider, Bernard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681991/
https://www.ncbi.nlm.nih.gov/pubmed/33225991
http://dx.doi.org/10.1186/s40478-020-01069-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681991/
https://www.ncbi.nlm.nih.gov/pubmed/33225991
http://dx.doi.org/10.1186/s40478-020-01069-3

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