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Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
The brain pathology of Alzheimer’s disease (AD) is characterized by the misfolding and aggregation of both the amyloid beta (Aβ) peptide and hyperphosphorylated forms of the tau protein. Initial Aβ deposition is considered to trigger a sequence of deleterious events contributing to tau pathology, ne...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681991/ https://www.ncbi.nlm.nih.gov/pubmed/33225991 http://dx.doi.org/10.1186/s40478-020-01069-3 |