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The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

BACKGROUND: Circular RNA (circRNAs) and hypoxia have been found to play the key roles in the pathogenesis and progression of cancer including colorectal cancer (CRC). However, the expressions and functions of the specific circRNAs in regulating hypoxia-involved CRC metastasis, and the circRNAs that...

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Detalles Bibliográficos
Autores principales: Chen, Liang-Yan, Wang, Lian, Ren, Yue-Xiang, Pang, Zheng, Liu, Yao, Sun, Xiao-Dong, Tu, Jian, Zhi, Zheng, Qin, Yan, Sun, Li-Na, Li, Jian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682012/
https://www.ncbi.nlm.nih.gov/pubmed/33225938
http://dx.doi.org/10.1186/s12943-020-01272-9